Why is Nitrogen So Important? Pharmaceutical manufacturers depend on nitrogen (N2), an abundant, inert gas that makes up 78% of the air we breathe, for many essential processes, including mixing raw materials, cryogenic grinding with liquid nitrogen to produce ultra-fine particles, and purging oxygen from packaging, thereby protecting product stability, extending shelf life, and ensuring […]
Magnetic Resonance Imaging (MRI) equipment is a diagnostic tool used in healthcare facilities. While most MRI safety focuses on magnetic field hazards, helium leaks present a less visible risk to both personnel and equipment. Liquid helium is necessary for MRI operation, but when released into an enclosed MRI suite, it can rapidly displace oxygen, creating […]
On January 31, 2022, a fire at a North Carolina fertilizer manufacturing facility caused officials to urge residents living nearby to stay away from their homes due to an increased risk of a possible explosion at the facility. People with respiratory issues were likewise advised to take precautions to minimize their potential exposure to toxic […]
What is Chlorine? Chlorine gas (Cl2) is a dense, yellow-green gas that has a distinctive, irritating odor that is similar to bleach and is almost instantly noticeable even at very low concentrations. While Cl2 is not flammable, it may react explosively when exposed to other gases, including acetylene, ether, ammonia, natural gas, and hydrogen, among […]
What is Oxygen Deficiency? The air we breathe is made up of 78% nitrogen, 21% oxygen, and trace amounts of other gases such as carbon dioxide, neon, and hydrogen. The Occupational Safety and Health Administration (OSHA) defines an environment in which oxygen levels fall below 19.5% as an oxygen-deficient atmosphere, which should be treated as […]
What is Carbon Dioxide? Carbon dioxide is the fourth most abundant gas in the earth’s atmosphere after nitrogen, oxygen, and argon. At room temperature, carbon dioxide (CO2) is a colorless, odorless, non-flammable gas, but at different temperatures and pressures, carbon dioxide can be a liquid or a solid (i.e., dry ice). Carbon dioxide is produced […]
In an effort to prevent boiler room accidents due to elevated levels of carbon monoxide, the Texas Department of Licensing and Regulation (TDLR) has adopted new regulations regarding carbon monoxide (CO) gas detection equipment that is used in boiler rooms built on or after September 1, 2020.
The manufacture of pharmaceutical products is a complex and multi-stage operation that can include processes such as blending, wet and dry granulation, milling, hot-melt extrusion, coating, and tablet pressing. Producing the exact formulation, release rate, consistency, and dosage form requires many chemical compounds and substances. Among the mare active pharmaceutical ingredients (API), the primary and […]
Centuries ago, merchants and shippers would place a lit candle inside barrels used to store biscuits before closing the lid. The idea was that the candle flame would deplete the oxygen inside the barrel to help keep the biscuits from spoiling. These days, the candle flame has been replaced by processes called Modified Atmosphere Packaging […]
In December 2020, two employees working at a Vernon, California food processing plant lost consciousness and died following an apparent liquid nitrogen leak. On January 28, 2021, there were several fatalities, and many other employees became sick, after being exposed to nitrogen gas when a liquid nitrogen line ruptured at a food processing plant in […]
There are several potential COVID-19 vaccines that may soon be available for widespread distribution. In particular, the United Kingdom has recently approved Pfizer’s vaccine, and the U.S. Food and Drug Administration is considering extending Emergency Use Authorization to the Pfizer and Moderna vaccines. That is certainly promising news, but storage, transportation, and delivery of these […]
What is an Oxygen Deficient Environment? The Occupational Safety and Health Administration (OSHA) defines an environment in which oxygen levels fall below 19.5 percent as an oxygen-deficient atmosphere, which should be treated as immediately dangerous to health or life. When there is not enough oxygen in the air, persons within the affected area may become […]
In modern times, vaccines have been widely used to keep people healthy by protecting them from serious illnesses and diseases. Worldwide, vaccines annually prevent millions of deaths, and their utilization is responsible, in many parts of the globe, for the nearly total eradication of numerous diseases, including polio, measles, and smallpox. According to the U.S. […]
MRI Magnetic resonance imaging (MRI) is a diagnostic procedure that uses a combination of a very large magnet, radio waves, and a computer to produce detailed, cross-sectional, and three-dimensional images of organs and structures within the body. An MRI scan is a valuable diagnostic tool that can show injuries or other anomalies that cannot be […]
